Era Test

The Endometrial Receptivity Analysis (ERA) test is a diagnostic tool used in fertility treatments to evaluate the best time for embryo implantation in the uterus. It helps determine the optimal window of implantation (WOI), which is crucial for improving the chances of a successful pregnancy in patients undergoing in vitro fertilization (IVF).

Here's a detailed overview of the ERA test:

The main goal of the ERA test is to assess the receptivity of the endometrium (the lining of the uterus) to ensure that an embryo is transferred at the most opportune time. This is especially useful for patients who have experienced recurrent implantation failure despite having good-quality embryos.

1. Endometrial Biopsy: 

A small sample of the endometrial tissue is collected. This is typically done around the time when the embryo would be transferred in a regular IVF cycle. The timing of the biopsy is critical and is usually performed after hormone preparation that mimics the natural menstrual cycle or during a mock cycle.A small sample of the endometrial tissue is collected. This is typically done around the time when the embryo would be transferred in a regular IVF cycle. The timing of the biopsy is critical and is usually performed after hormone preparation that mimics the natural menstrual cycle or during a mock cycle.

2. Genetic Analysis: 

The collected tissue is sent to a specialized laboratory where the expression of over 200 genes related to endometrial receptivity is analyzed using next-generation sequencing (NGS).

3. Results: 

Based on the gene expression profile, the test identifies whether the endometrium is receptive, pre-receptive, or post-receptive.

Receptive: Indicates the endometrium is ready for implantation.

Pre-receptive: Suggests that the endometrium is not yet ready for implantation.

Post-receptive: Indicates the endometrium has passed the optimal window for implantation.

Personalized Timing: 

It helps in personalizing the timing of embryo transfer, thereby increasing the chances of successful implantation.

Reduced Implantation Failures: 

For patients with repeated implantation failures, the ERA test can identify if the issue is related to the timing of the embryo transfer.

Enhanced IVF Success Rates: 

By determining the optimal window for embryo transfer, the ERA test can potentially enhance the overall success rates of IVF treatments.

• Patients with a history of recurrent implantation failure.
• Patients undergoing IVF who have not had successful implantation despite transferring good-quality embryos.
• Patients with unexplained infertility where timing issues might be suspected.

Preparation: 

The patient undergoes a cycle mimicking the natural cycle or a hormone replacement therapy (HRT) cycle.

Biopsy: 

The endometrial biopsy is usually performed on day 19-21 of the menstrual cycle (in a 28-day cycle) or as per the doctor's recommendation based on the individual's cycle.

Analysis and Results: 

The results are typically available within a couple of weeks. Based on the findings, the doctor will adjust the timing of the embryo transfer in subsequent IVF cycles.

• The ERA test is an additional procedure and can increase the cost and time of fertility treatment.
• It may require a mock cycle, which means an additional cycle before the actual IVF cycle.

The ERA test can be a valuable tool in optimizing the timing of embryo transfer, thereby improving the chances of successful pregnancy for those undergoing fertility treatments.might be suspected.

Over 2000+ Happy Families 

People Recommend Us !

• We provide individualized treatment plan, care and attention to every couple during their journey to Parenthood. 
• We offer high success rates of more than 85% for IVF - ICSI and Surrogacy programs. 
• Best In Class Pregnancy Rate
• All Inclusive IVF Packages
• Affordable and Transparent Pricing
• Hassle free service experience 
• Accessible and Approachable 
• 95% Patient Satisfaction Score