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Genessa Fertility & Women Health

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PESA (Percutaneous Epididymal Sperm Aspiration)

PESA Procedure

What is PESA (Percutaneous Epididymal Sperm Aspiration) ?

PESA stands for Percutaneous Epididymal Sperm Aspiration. It's a procedure used in infertility treatment to retrieve sperm from the epididymis, a coiled tube at the back of the testicle where sperm is stored. This is a procedure used particularly in cases where a male partner has obstructive azoospermia, a condition where sperm is produced but blocked from being ejaculated due to a blockage in the epididymis or other parts of the male reproductive tract.


Key Points About PESA

1. Procedure:

PESA is a minimally invasive procedure performed under local anesthesia.A fine needle is inserted into the epididymis (a tube where sperm matures and is stored) to aspirate (suction out) sperm.The procedure is typically quick, taking about 20-30 minutes.


2. Usage:

The collected sperm is usually used for Intra-Cytoplasmic Sperm Injection (ICSI), a specialized form of In Vitro Fertilization (IVF) where a single sperm is injected directly into an egg.PESA can be an alternative to more invasive procedures like Testicular Sperm Extraction (TESE).


3. Indications:

Obstructive azoospermia due to congenital absence of the vas deferens, prior vasectomy, or other blockages.In some cases, PESA can also be used in non-obstructive azoospermia, though success rates may vary.


4. Success Rates:

The success of PESA largely depends on the cause of azoospermia and the skill of the performing urologist.Success rates for subsequent fertilization and pregnancy depend on factors including the quality of the retrieved sperm and the female partner's reproductive health.


5. Recovery:

Recovery from PESA is typically quick, with minimal discomfort and risks.Complications are rare but can include infection or bleeding.


6. Advantages:

Less invasive than surgical retrieval methods.Lower risk of complications and quicker recovery time.Can often be performed on an outpatient basis.


When PESA is Recommended

  • Obstructive azoospermia:  PESA is recommended for men with obstructive azoospermia as a first-line method to retrieve sperm. This condition occurs when sperm is produced normally but can't be transported due to a blockage in the reproductive tract.
  • Congenital absence of the vas deferens (CAVD): This is a birth defect where the vas deferens is missing or underdeveloped.
  • Vasectomy reversal failure: When a vasectomy reversal procedure is unsuccessful.
  • It can also be considered when other methods of sperm retrieval have failed or when non-obstructive azoospermia is present, but alternative approaches are more commonly used in these cases.


Overall, PESA is a valuable tool in the arsenal of fertility treatments, offering a less invasive option for sperm retrieval that can help couples achieve pregnancy through assisted reproductive technologies like ICSI and IVF.


The PESA Procedure

  • Local anesthesia: The procedure is usually performed under local anesthesia.
  • Needle insertion: A small needle is inserted into the epididymis.
  • Sperm extraction: Suction is applied through the needle to extract sperm.
  • Sperm preparation: The extracted sperm is then prepared in a laboratory for use in assisted reproductive technologies (ART) like IVF or ICSI.


Success Rates and Risks

  • Success rates: The success of PESA depends on several factors, including the cause of infertility, the quality of the retrieved sperm, and the chosen ART method.
  • Risks: While generally safe, PESA carries some risks, such as infection, bleeding, and pain.


Alternatives to PESA

  • TESA (Testicular Sperm Aspiration): Involves extracting sperm directly from the testicles.
  • MESA (Microsurgical Epididymal Sperm Aspiration): A more complex procedure involving a small incision to access the epididymis.


It's important to consult with a fertility specialist to determine the most appropriate treatment option based on your specific condition.


Would you like to know more about the other sperm retrieval methods or the IVF/ICSI process?


Share your questions and concerns with us on info@genessaivf.com 

Call or message us on - (+91) 9871977367 

Future of PESA PROCEDURE

The future of PESA (Percutaneous Epididymal Sperm Aspiration) is likely to be influenced by several factors:

Advancements in Technology

  • Image-guided PESA: Real-time imaging techniques could improve the accuracy and efficiency of sperm retrieval.
  • Microfluidics: This technology might be used to enhance sperm processing and selection after extraction.

Development of Alternative Techniques

  • PESA combined with other procedures: Integration with other techniques like micro-TESA (Testicular Sperm Aspiration) could increase the chances of sperm retrieval.
  • Non-invasive sperm retrieval: While still in its early stages, research into non-invasive methods could potentially replace PESA in the future.

Personalized Medicine and Genetic Testing

  • Sperm selection: Advances in genetic testing might enable the selection of sperm with optimal genetic characteristics before fertilization.
  • Tailored treatments: Personalized medicine could lead to more effective PESA protocols based on individual patient factors.

Ethical Considerations

  • Sperm banking: Ethical discussions about sperm banking and its implications for future generations will continue.
  • Informed consent: Ensuring patients fully understand the risks and benefits of PESA will remain crucial.


Overall, the future of PESA holds promise for improved success rates and less invasive procedures. However, it is essential to balance technological advancements with ethical considerations to ensure the best outcomes for patients.


Would you like to know more about a specific aspect of PESA's future, such as the potential impact of artificial intelligence or the role of stem cell research?


Share your questions and concerns with us on info@genessaivf.com 

Call or message us on - (+91) 9871977367 

Why Choose Us?

Over 2000+ Happy Families 

People Recommend Us !


  • We provide individualized treatment plan, care and attention to every couple during their journey to Parenthood. 
  • We offer high success rates of more than 85% for IVF - ICSI and Surrogacy programs. 
  • Best In Class Pregnancy Rate
  • All Inclusive IVF Packages
  • Affordable and Transparent Pricing
  • Hassle free service experience 
  • Accessible and Approachable 
  • 95% Patient Satisfaction Score 


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Genessa Fertility and Women Health's content is for informational and educational purposes only. 

Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

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